Resource CodeSystem/FHIR Server from package rki.demis.igs#3.0.0 (156 ms)

Resources that use this resource

ValueSet
sequencingStrategy	Sequenzierungsstrategie

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Source

{
  "resourceType" : "CodeSystem",
  "id" : "sequencingStrategy",
  "url" : "https://demis.rki.de/fhir/igs/CodeSystem/sequencingStrategy",
  "version" : "2.0.0",
  "name" : "SequencingStrategy",
  "title" : "Sequenzierungsstrategie",
  "status" : "active",
  "experimental" : false,
  "date" : "2024-07-24",
  "publisher" : "Robert Koch-Institut",
  "description" : "Das CodeSystem SequencingStrategy enthält die Codes der Sequenzierungsstrategien (angelehnt an ENA).",
  "caseSensitive" : false,
  "valueSet" : "https://demis.rki.de/fhir/igs/ValueSet/sequencingStrategy",
  "content" : "complete",
  "count" : 36,
  "concept" : [
    {
      "code" : "wgs",
      "display" : "Whole Genome Sequencing - random sequencing of the whole genome (see pubmed 10731132 for details)"
    },
    {
      "code" : "wga",
      "display" : "Whole Genome Amplification followed by random sequencing. (see pubmed 1631067,8962113 for details)"
    },
    {
      "code" : "wxs",
      "display" : "Random sequencing of exonic regions selected from the genome. (see pubmed 20111037 for details)"
    },
    {
      "code" : "rna-seq",
      "display" : "Random sequencing of whole transcriptome, also known as Whole Transcriptome Shotgun Sequencing, or WTSS). (see pubmed 18611170 for details)"
    },
    {
      "code" : "ssrna-seq",
      "display" : "Strand-specific RNA sequencing."
    },
    {
      "code" : "mirna-seq",
      "display" : "Micro RNA sequencing strategy designed to capture post-transcriptional RNA elements and include non-coding functional elements. (see pubmed 21787409 for details)"
    },
    {
      "code" : "ncrna-seq",
      "display" : "Capture of other non-coding RNA types, including post-translation modification types such as snRNA (small nuclear RNA) or snoRNA (small nucleolar RNA), or expression regulation types such as siRNA (small interfering RNA) or piRNA/piwi/RNA (piwi-interacting RNA)."
    },
    {
      "code" : "fl-cdna",
      "display" : "Full-length sequencing of cDNA templates"
    },
    {
      "code" : "est",
      "display" : "Single pass sequencing of cDNA templates"
    },
    {
      "code" : "hi-c",
      "display" : "Chromosome Conformation Capture technique where a biotin-labeled nucleotide is incorporated at the ligation junction, enabling selective purification of chimeric DNA ligation junctions followed by deep sequencing."
    },
    {
      "code" : "atac-seq",
      "display" : "Assay for Transposase-Accessible Chromatin (ATAC) strategy is used to study genome-wide chromatin accessibility. alternative method to DNase-seq that uses an engineered Tn5 transposase to cleave DNA and to integrate primer DNA sequences into the cleaved genomic DNA."
    },
    {
      "code" : "wcs",
      "display" : "Random sequencing of a whole chromosome or other replicon isolated from a genome."
    },
    {
      "code" : "rad-seq",
      "display" : "RAD sequencing"
    },
    {
      "code" : "clone",
      "display" : "Genomic clone based (hierarchical) sequencing."
    },
    {
      "code" : "poolclone",
      "display" : "Shotgun of pooled clones (usually BACs and Fosmids)."
    },
    {
      "code" : "amplicon",
      "display" : "Sequencing of overlapping or distinct PCR or RT-PCR products. For example, metagenomic community profiling using SSU rRNA."
    },
    {
      "code" : "cloneend",
      "display" : "Clone end (5’, 3’, or both) sequencing."
    },
    {
      "code" : "finishing",
      "display" : "Sequencing intended to finish (close) gaps in existing coverage."
    },
    {
      "code" : "chip-seq",
      "display" : "ChIP-seq, Chromatin ImmunoPrecipitation, reveals binding sites of specific proteins, typically transcription factors (TFs) using antibodies to extract DNA fragments bound to the target protein."
    },
    {
      "code" : "mnase-seq",
      "display" : "Identifies well-positioned nucleosomes. uses Micrococcal Nuclease (MNase) is an endo-exonuclease that processively digests DNA until an obstruction, such as a nucleosome, is reached."
    },
    {
      "code" : "dnase-hypersensitivity",
      "display" : "Sequencing of hypersensitive sites, or segments of open chromatin that are more readily cleaved by DNaseI."
    },
    {
      "code" : "bisulfite-seq",
      "display" : "MethylC-seq. Sequencing following treatment of DNA with bisulfite to convert cytosine residues to uracil depending on methylation status."
    },
    {
      "code" : "cts",
      "display" : "Concatenated Tag Sequencing"
    },
    {
      "code" : "mre-seq",
      "display" : "Methylation-Sensitive Restriction Enzyme Sequencing."
    },
    {
      "code" : "medip-seq",
      "display" : "Methylated DNA Immunoprecipitation Sequencing."
    },
    {
      "code" : "mbd-seq",
      "display" : "Methyl CpG Binding Domain Sequencing."
    },
    {
      "code" : "tn-seq",
      "display" : "Quantitatively determine fitness of bacterial genes based on how many times a purposely seeded transposon gets inserted into each gene of a colony after some time."
    },
    {
      "code" : "validation",
      "display" : "CGHub special request"
    },
    {
      "code" : "faire-seq",
      "display" : "Formaldehyde Assisted Isolation of Regulatory Elements. Reveals regions of open chromatin."
    },
    {
      "code" : "selex",
      "display" : "Systematic Evolution of Ligands by Exponential enrichment"
    },
    {
      "code" : "rip-seq",
      "display" : "Direct sequencing of RNA immunoprecipitates (includes CLIP-Seq, HITS-CLIP and PAR-CLIP)."
    },
    {
      "code" : "chia-pet",
      "display" : "Direct sequencing of proximity-ligated chromatin immunoprecipitates."
    },
    {
      "code" : "synthetic-long-read",
      "display" : "binning and barcoding of large DNA fragments to facilitate assembly of the fragment"
    },
    {
      "code" : "targeted-capture",
      "display" : "Enrichment of a targeted subset of loci."
    },
    {
      "code" : "tethered-chromatin-conformation-capture",
      "display" : "Tethered Chromatin Conformation Capture"
    },
    {
      "code" : "other",
      "display" : "Library strategy not listed."
    }
  ],
  "text" : {
  }
}

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